Sustainability & Environment

We take responsibility. For your skin. And our planet.

Learn more about our sustainability program

Foldingbox made of FSC certified paper

About

An Epigenetic Day Care SPF 30 enriched with Epicelline®, based on patented Age Clock Technology, proven to visibly reverse the signs of ageing for younger‑looking skin, while helping to protect against advanced skin ageing.
NART: 99628-09900-00

Our breakthrough anti-age innovation  

Anti-ageing Day Care SPF 30, reverses signs of skin ageing visibly and protects against advanced skin ageing.

Skin ageing is accelerated by lifestyle and environmental factors that change the skin’s epigenetic patterns. This means that youth genes are deactivated, leading to visible signs of ageing.  

After 15 years of epigenetic research, Eucerin has discovered how to reactivate these youth genes based on a patented Age Clock Technology: 

Epicelline® helps to reactivate the skin’s youth genes and allows skin cells to act younger. This mechanism makes the skin look younger than its age and reverses 10 signs of ageing, visibly leading to:  

  • Wrinkles reduction
  • Firmness increase
  • Lfiting effect
  • Pores
  • Fine line reduction
  • Hydration
  • Rejuvenation
  • Radiance
  • Smoothness
  • Evenness

Disclaimer: Clinical study over 2 weeks with 42 volunteers and clincal studies over 4 weeks with 40 and 52 volunteers respectively. 

How to Use

Apply the Day Care SPF 30 as the first step in the morning. For advanced efficacy with 3x power, combine with the Eucerin Epigenetic Serum and Night Care.

BUILD YOUR OWN SKIN PROTOCOL

Deep Rejuvenation
Apply the Hyaluron‑Filler + Longevity Epigenetic Serum morning and evening to a thoroughly cleansed face. Apply to the face, neck and décolleté, gently massaging into the skin.
Go to Product
Prevent Photoaging
In the morning, apply 1–2 pumps of the Hyaluron‑Filler + Longevity Epigenetic Day Care SPF 30 to the face, neck and décolleté, gently massaging into the skin.
Go to Product
Overnight Regeneration
Apply the Hyaluron-Filler + Longevity Epigenetic Night Care in the evening on your face, neck and décolleté by gently massaging it into the skin.
Go to Product

Main findings

*Product-in-use test with 400* and 160 ** volunteers over 4 weeks. *** Product-in-use test with 400 volunteers over 4 weeks
100%
Confirm deep skin rejuvenation*
98%
Confirm reduced wrinkles**
98%
Confirm youger-looking skin**
100%
confirm lifting-effect on skin after 4 weeks***

Clinical Formula

Hyaluronic acid

Hyaluronic Acid is formed by skin cells and is part of the connective tissue of the skin. One of its key functions is to retain moisture, and it has the ability to bind in between 1,000 and 10,000 times its own weight in water (i.e. one gram binds between one and ten liters). As we age, the skin's natural ability to produce Hyaluronic Acid depletes and wrinkles start to form and deepen.

Learn More
Glycine Saponin

Glycine Saponin, also known as Glycine Soja Germ Extract, is an active ingredient extracted from the soya bean. It is one of the most effective stimulators of Hyaluronic Acid in cells in the dermal layer of skin and has been proven to increase Hyaluronic Acid production by up to 256% on cell level*.

* Study report: Saponins – a new generation of Hyaluronan-stimulating actives for human skin, S. Gallinat, F. Rippke, C. Keppler, J. Mergell, A. Bürger, F. Stäb, H.Wenck Beiersdorf AG, Hamburg, Germany

Learn More
Enoxolone

Enoxolone, also known as Glycyrrhetinic Acid, is derived from the roots of Glycyrrhiza glabra (liquorice plant) and is well known in traditional Chinese medicine. It is a pentacyclic triterpenoid with anti‑inflammatory and antimicrobial properties. 

Enoxolone helps preserve levels of Hyaluronic Acid and elastin by protecting them against enzymatic degradation by hyaluronidase, and supports the skin’s own repair mechanisms against UV‑induced DNA damage.

Learn More
Dihydromyricetin (Epicelline®)
An innovative active ingredient that helps to reactivate the skin’s youth genes by making skin cells act younger. 
Learn More
Hyaluronic acid

Hyaluronic Acid is formed by skin cells and is part of the connective tissue of the skin. One of its key functions is to retain moisture, and it has the ability to bind in between 1,000 and 10,000 times its own weight in water (i.e. one gram binds between one and ten liters). As we age, the skin's natural ability to produce Hyaluronic Acid depletes and wrinkles start to form and deepen.

Learn More
Glycine Saponin

Glycine Saponin, also known as Glycine Soja Germ Extract, is an active ingredient extracted from the soya bean. It is one of the most effective stimulators of Hyaluronic Acid in cells in the dermal layer of skin and has been proven to increase Hyaluronic Acid production by up to 256% on cell level*.

* Study report: Saponins – a new generation of Hyaluronan-stimulating actives for human skin, S. Gallinat, F. Rippke, C. Keppler, J. Mergell, A. Bürger, F. Stäb, H.Wenck Beiersdorf AG, Hamburg, Germany

Learn More
Enoxolone

Enoxolone, also known as Glycyrrhetinic Acid, is derived from the roots of Glycyrrhiza glabra (liquorice plant) and is well known in traditional Chinese medicine. It is a pentacyclic triterpenoid with anti‑inflammatory and antimicrobial properties. 

Enoxolone helps preserve levels of Hyaluronic Acid and elastin by protecting them against enzymatic degradation by hyaluronidase, and supports the skin’s own repair mechanisms against UV‑induced DNA damage.

Learn More
Dihydromyricetin (Epicelline®)
An innovative active ingredient that helps to reactivate the skin’s youth genes by making skin cells act younger. 
Learn More
Hyaluronic acid

Hyaluronic Acid is formed by skin cells and is part of the connective tissue of the skin. One of its key functions is to retain moisture, and it has the ability to bind in between 1,000 and 10,000 times its own weight in water (i.e. one gram binds between one and ten liters). As we age, the skin's natural ability to produce Hyaluronic Acid depletes and wrinkles start to form and deepen.

Learn More
Glycine Saponin

Glycine Saponin, also known as Glycine Soja Germ Extract, is an active ingredient extracted from the soya bean. It is one of the most effective stimulators of Hyaluronic Acid in cells in the dermal layer of skin and has been proven to increase Hyaluronic Acid production by up to 256% on cell level*.

* Study report: Saponins – a new generation of Hyaluronan-stimulating actives for human skin, S. Gallinat, F. Rippke, C. Keppler, J. Mergell, A. Bürger, F. Stäb, H.Wenck Beiersdorf AG, Hamburg, Germany

Learn More
Enoxolone

Enoxolone, also known as Glycyrrhetinic Acid, is derived from the roots of Glycyrrhiza glabra (liquorice plant) and is well known in traditional Chinese medicine. It is a pentacyclic triterpenoid with anti‑inflammatory and antimicrobial properties. 

Enoxolone helps preserve levels of Hyaluronic Acid and elastin by protecting them against enzymatic degradation by hyaluronidase, and supports the skin’s own repair mechanisms against UV‑induced DNA damage.

Learn More
View all
FAQ

What is epigenetics and how does it affect the skin?

Epigenetics explores how genes operate and how one’s lifestyle influences them, ultimately leading to signs of skin ageing. After 15 years of research, Eucerin scientists have found that these epigenetic changes determining your skin age can be reversed through targeted epigenetic skincare solutions.

What is Eucerin’s patented Age Clock Technology?

Patented Age Clock Technology is a novel algorithm based on the epigenetic patterns of young and aged skin, which can measure the skin’s biological age. This groundbreaking technology also enabled Eucerin scientists to discover the active ingredient Epicelline®.

What age should I start using the Epigenetic Day Care SPF 30?

While skin ages differently depending on genetics and lifestyle, signs of ageing typically begin to appear in the late twenties and early thirties. This is why we recommend starting to use the Epigenetic Day Care SPF 30 at this stage.

Can I apply the Epigenetic Day Care SPF 30 to the entire face or only to specific areas?

The Day Care SPF 30 can be applied liberally to the entire face, neck and décolleté. Avoid contact with the eyes.

You may also like

Read also some related articles

Epigenetic clock

Patented Age Clock Technology: Eucerin can now reverse the skin's biological age

5 min read
Epigenetics meaning
Ageing skin

Epigenetics: The Innovative Science Behind Eucerin’s Latest Research

4 min read

Epigenetic Day Care with UV protection for ageing skin

Hyaluron-Filler + Longevity Epigenetic Day Care SPF30

Hyaluron-Filler + Longevity

Hyaluron-Filler + Longevity Epigenetic Serum

SPF 50+

Photoageing

Photoageing Control Sun Fluid SPF50

Epigenetic Day Care with UV protection for ageing skin

Hyaluron-Filler + Longevity Epigenetic Day Care SPF30

Hyaluron-Filler + Longevity

Hyaluron-Filler + Longevity Epigenetic Serum

SPF 50+

Photoageing

Photoageing Control Sun Fluid SPF50

Epigenetic Day Care with UV protection for ageing skin

Hyaluron-Filler + Longevity Epigenetic Day Care SPF30

Hyaluron-Filler + Longevity

Hyaluron-Filler + Longevity Epigenetic Serum

SPF 50+

Photoageing

Photoageing Control Sun Fluid SPF50

4.3
from 53 reviews*
Write Review
    08/08/2026
    All day hydration
    Really easy to use. Pump bottle allows you to control how much you use. Provides all day hydration and added benefit of SPF. Keeps my skin soft and smooth. It’s a silky smooth texture and absorbs into my skin well. Leaves my skin looking healthy and plump. Product is a decent size and will last me a good amount of time. Only critique is a full pump gives you a lot of product which can be too much. It’s silky texture and added SPF means it takes a bit more time than a regular moisturiser to fully absorb into the skin.
    Courtd5
    Sample: Free sample provided
    07/08/2026
    Hydration in a tube
    I was sceptical at first that I wouldn’t see a difference but wow was I wrong! From the first use I could feel the difference on my skin. My skin felt tighter but more hydrated this is definitely a staple product & i will buying more
    Review photo 1
    Jodie10
    Sample: Free sample provided
    07/08/2026
    Very nice!
    I’ve used this suncream for just over a month now and I’m very impressed. My skin can be quite sensitive when it comes to sunscreens but I’ve had no problems at all. I’ve been applying it under makeup each morning and it’s lasted all day without sliding around. The formula is very thick but doesn’t feel heavy or greasy on my skin and it doesn’t leave me with pimples. I’ve noticed my skin feels and looks firmer and more radiant and I’m really happy with how many skincare benefits are in this suncream. Overall it’s done exactly what it needs to do and protected me from the sun while having multiple other skincare benefits. I would highly recommend.
    Review photo 1
    Becky099
    Sample: Free sample provided
See all
*Reviews are not verified for authenticity
Hyaluron-Filler + Longevity

Hyaluron-Filler + Longevity Epigenetic Day Care SPF30

  • 4.3
    53 reviews
Skin concerns
Sun ProtectionAgeing skin
Key Benefits
  • Visibly reverses 10 signs of ageing
  • Provides long‑lasting, deep hydration
  • Helps protect against advanced skin ageing for younger‑looking skin
Read More
Key Ingredients

Dihydromyricetin (Epicelline®), Hyaluronic acid, Glycine Saponin

Learn More
Size
50 ml
Find a pharmacy