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About

A clinically tested epigenetic anti‑ageing Night Care, based on patented Age Clock Technology with the active ingredient Epicelline®, proven to visibly reverse the signs of ageing for firmer, younger‑looking skin and to help regenerate the skin overnight.
NART: 99630-09900-00

Our breakthrough anti-age Night Care innovation

Anti-ageing Night Care, reverses signs of skin ageing visibly and regenerates the skin overnight.

Skin ageing is accelerated by lifestyle and environmental factors that change the skin’s epigenetic patterns. This means that youth genes are deactivated, leading to visible signs of ageing. 

After 17 years of epigenetic research, Eucerin has discovered how to reactivate these youth genes based on a patented Age Clock Technology: 

Epicelline® helps to reactivate the skin’s youth genes and allows skin cells to act younger. This mechanism makes the skin look younger than its age and reverses 10 signs of ageing, visibly leading to: 

  • Wrinkles reduction
  • Firmness increase
  • Lifting effect
  • Facial contours sharpened
  • Fine line reduction
  • Hydration
  • Rejuvenation
  • Radiance
  • Smoothness
  • Evenness

Formulated with Provitamin B5, it supports the skin regeneration overnight.  

Disclaimer: Clinical study over 2 weeks with 41 volunteers and clinical studies over 4 weeks with 44 and 55 volunteers respectively.

How to Use

Apply the Night Care in the evening. For advanced efficacy with 3x power, combine with the Eucerin Epigenetic Serum and Day Care SPF 30 in the morning.

BUILD YOUR OWN ACNE PRONE SKIN PROTOCOL

Prevent Photoaging
In the morning, apply 1–2 pumps of the Hyaluron‑Filler + Longevity Epigenetic Day Care SPF 30 to the face, neck and décolleté, gently massaging into the skin.
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Main findings

*Product-in-use test with 400 volunteers over 4 weeks. **Product-in-use test with 400 volunteers over 4 weeks.
100%
Confirm regenerated skin*
97%
Confirm visibly reduced wrinkles*
99%
Comfirm youthful-looking skin*
96%
Confirm redefined facial contours after 4 weeks**

Clinical Formula

Pro Vitamin B5

Provitamin B5, also known as Panthenol, is a precursor to vitamin B5. Panthenol participates in numerous metabolic processes (e.g., energy production, synthesis of fatty acids) and helps improve hydration in the outermost layers of the skin. It helps maintain moisture, supports skin barrier regeneration, and prevents dryness and irritation. When applied regularly, it has been proven to significantly improve symptoms of skin irritation such as dryness, roughness, scaling, and redness. It also provides benefits in improving skin firmness.

Well absorbed by the skin, it supports regeneration, stimulates epithelialisation and wound healing, and alleviates irritation and inflammation.

Learn More
Glycine Saponin

Glycine Saponin, also known as Glycine Soja Germ Extract, is an active ingredient extracted from the soya bean. It is one of the most effective stimulators of Hyaluronic Acid in cells in the dermal layer of skin and has been proven to increase Hyaluronic Acid production by up to 256% on cell level*.

* Study report: Saponins – a new generation of Hyaluronan-stimulating actives for human skin, S. Gallinat, F. Rippke, C. Keppler, J. Mergell, A. Bürger, F. Stäb, H.Wenck Beiersdorf AG, Hamburg, Germany

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Enoxolone

Enoxolone, also known as Glycyrrhetinic Acid, is derived from the roots of Glycyrrhiza glabra (liquorice plant) and is well known in traditional Chinese medicine. It is a pentacyclic triterpenoid with anti‑inflammatory and antimicrobial properties. 

Enoxolone helps preserve levels of Hyaluronic Acid and elastin by protecting them against enzymatic degradation by hyaluronidase, and supports the skin’s own repair mechanisms against UV‑induced DNA damage.

Learn More
Dihydromyricetin (Epicelline®)
An innovative active ingredient that helps to reactivate the skin’s youth genes by making skin cells act younger. 
Learn More
Pro Vitamin B5

Provitamin B5, also known as Panthenol, is a precursor to vitamin B5. Panthenol participates in numerous metabolic processes (e.g., energy production, synthesis of fatty acids) and helps improve hydration in the outermost layers of the skin. It helps maintain moisture, supports skin barrier regeneration, and prevents dryness and irritation. When applied regularly, it has been proven to significantly improve symptoms of skin irritation such as dryness, roughness, scaling, and redness. It also provides benefits in improving skin firmness.

Well absorbed by the skin, it supports regeneration, stimulates epithelialisation and wound healing, and alleviates irritation and inflammation.

Learn More
Glycine Saponin

Glycine Saponin, also known as Glycine Soja Germ Extract, is an active ingredient extracted from the soya bean. It is one of the most effective stimulators of Hyaluronic Acid in cells in the dermal layer of skin and has been proven to increase Hyaluronic Acid production by up to 256% on cell level*.

* Study report: Saponins – a new generation of Hyaluronan-stimulating actives for human skin, S. Gallinat, F. Rippke, C. Keppler, J. Mergell, A. Bürger, F. Stäb, H.Wenck Beiersdorf AG, Hamburg, Germany

Learn More
Enoxolone

Enoxolone, also known as Glycyrrhetinic Acid, is derived from the roots of Glycyrrhiza glabra (liquorice plant) and is well known in traditional Chinese medicine. It is a pentacyclic triterpenoid with anti‑inflammatory and antimicrobial properties. 

Enoxolone helps preserve levels of Hyaluronic Acid and elastin by protecting them against enzymatic degradation by hyaluronidase, and supports the skin’s own repair mechanisms against UV‑induced DNA damage.

Learn More
Dihydromyricetin (Epicelline®)
An innovative active ingredient that helps to reactivate the skin’s youth genes by making skin cells act younger. 
Learn More
Pro Vitamin B5

Provitamin B5, also known as Panthenol, is a precursor to vitamin B5. Panthenol participates in numerous metabolic processes (e.g., energy production, synthesis of fatty acids) and helps improve hydration in the outermost layers of the skin. It helps maintain moisture, supports skin barrier regeneration, and prevents dryness and irritation. When applied regularly, it has been proven to significantly improve symptoms of skin irritation such as dryness, roughness, scaling, and redness. It also provides benefits in improving skin firmness.

Well absorbed by the skin, it supports regeneration, stimulates epithelialisation and wound healing, and alleviates irritation and inflammation.

Learn More
Glycine Saponin

Glycine Saponin, also known as Glycine Soja Germ Extract, is an active ingredient extracted from the soya bean. It is one of the most effective stimulators of Hyaluronic Acid in cells in the dermal layer of skin and has been proven to increase Hyaluronic Acid production by up to 256% on cell level*.

* Study report: Saponins – a new generation of Hyaluronan-stimulating actives for human skin, S. Gallinat, F. Rippke, C. Keppler, J. Mergell, A. Bürger, F. Stäb, H.Wenck Beiersdorf AG, Hamburg, Germany

Learn More
Enoxolone

Enoxolone, also known as Glycyrrhetinic Acid, is derived from the roots of Glycyrrhiza glabra (liquorice plant) and is well known in traditional Chinese medicine. It is a pentacyclic triterpenoid with anti‑inflammatory and antimicrobial properties. 

Enoxolone helps preserve levels of Hyaluronic Acid and elastin by protecting them against enzymatic degradation by hyaluronidase, and supports the skin’s own repair mechanisms against UV‑induced DNA damage.

Learn More
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FAQ

What is epigenetics and how does it affect the skin?

Epigenetics explores how genes operate and how one’s lifestyle influences them, ultimately leading to signs of skin ageing. After 15 years of research, Eucerin scientists have found that these epigenetic changes determining your skin age can be reversed through targeted epigenetic skincare solutions.

What is Eucerin’s patented Age Clock Technology?

Patented Age Clock Technology is a novel algorithm based on the epigenetic patterns of young and aged skin, which can measure the skin’s biological age. This groundbreaking technology also enabled Eucerin scientists to discover the active ingredient Epicelline®.

What age should I start using the Epigenetic Night Care?

While skin ages differently depending on genetics and lifestyle, signs of ageing typically begin to appear in the late twenties and early thirties. This is why we recommend starting to use the Epigenetic Night Care at this stage.

Can I apply the Epigenetic Night Care to the entire face or only to specific areas?

The Epigenetic Night Care can be applied liberally to the entire face, neck and décolleté. Avoid contact with the eyes.

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Hyaluron-Filler + Longevity

Hyaluron-Filler + Longevity Epigenetic Serum

Hyaluron-Filler + Longevity

Hyaluron-Filler + Longevity Epigenetic Serum

Hyaluron-Filler + Longevity

Hyaluron-Filler + Longevity Epigenetic Serum

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Hyaluron-Filler + Longevity

Hyaluron-Filler + Longevity Epigenetic Night Care

Skin concerns
Ageing skin
Key Benefits
  • 100% confirm regenerated skin*
  • 97% confirm visibly reduced wrinkles
  • 99% confirm youthful-looking skin
  • Visible results in 4 weeks* *Product-in-use test with 400 volunteers over 4 weeks
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Key Ingredients

Dihydromyricetin (Epicelline®), Pro Vitamin B5, Glycine Saponin

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Size
50 ml
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