Ceramides are produced by the skin to create a natural protective barrier that helps prevent moisture loss due to evaporation, and to block out irritants that can cause inflammation and itching. When the skin’s ceramide levels fall, dryness and irritation can result. Ceramide-3 can be used as a synthetically produced biologically identical molecule that helps support and regenerate the skin’s natural barrier to lock in moisture and help prevent dryness and irritation.