• 1/8
  • 2/8
  • 3/8
  • 4/8
  • 5/8
  • 6/8
  • 7/8
  • 8/8
  • 1/8
  • 2/8
  • 3/8
  • 4/8
  • 5/8
  • 6/8
  • 7/8
  • 8/8

Eucerin Hyaluron-Filler Night Cream

104 reviews
Next generation Hyaluron Filler: Anti-ageing night cream with Hyaluronic Acid, Saponin and Enoxolone
For all skin types​
Concentrated Dexpanthenol supports the skin’s regeneration process overnight

Eucerin Hyaluron-Filler Night

Anti-ageing night cream with 3x Effect formula: 1 Fills. 2 Stimulates. 3 Defends. Counteracts the ageing process. For visibly smoother, radiant, and younger looking skin.

Product info

Anti-ageing night cream for all skin types As we age, our skin’s own production of Hyaluronic Acid decreases causing the skin to form wrinkles and look older. Eucerin Hyaluron-Filler Night with 3x Effect formula counteracts this process: Fills: High and low molecular acid moisturizes and plumps up wrinkles. Stimulates: The anti-oxidant, Saponin, activates the skin’s own Hyaluronic Acid production by up to 256% and protects the skin from free radicals. Defends: Enoxolone decreases the degradation rate of Hyaluronic-Acid by more than 50%. Eucerin Hyaluron-Filler Night addresses the first signs of ageing. It noticeably plumps up fine lines and even deep wrinkles for a rejuvenated look while supporting skin regeneration. Eucerin’s unique blend of high and low molecular Hyaluronic Acid, Glycine-saponin, and Enoxolone delivers a targeted approach to visibly plumping even deep wrinkles. High molecular Hyaluronic Acid improves hydration and smooths the outermost layers of skin while low molecular Hyaluronic Acid, which is 40 times smaller(1), penetrates further into the epidermal skin layers where deeper wrinkles originate. The anti-oxidant, Glycine Saponin, supports Hyaluronic Acid production in the dermal layer where the deepest wrinkles are formed and protects from free radicals. Enoxolone protects the skin’s own Hyaluron from degradation and Dexpanthenol supports skin’s overnight regeneration process. (1) Compared to the high molecular Hyaluronic Acid also used in the formula.

Clinical and dermatological studies

Very good skin tolerability and very good efficacy

Main findings


Fine lines and wrinkles are visibly reduced


Prevents the formation of new lines and wrinkles


Supports the skin's regeneration overnight


Has a very intense caring effect

(2) Beiersdorf AG, PiU Thailand, January 2021

How To Use


For your daily routine


Cleanse skin with Eucerin DematoClean Mild Cleansing Milk (for dry skin) or Eucerin DematoClean Refreshing Cleansing Gel (for normal to combintion skin). Use Eucerin DematoClean Waterproof Eye Make-up Remover, to remove any last traces of eye make-up.

Read More


Use Eucerin DematoClean Clarifying Toner to prepare skin for your care products.

Read More

Special Care

Apply Eucerin Hyaluron-Filler Night and Eucerin Hyaluron-Filler Eye SPF 15. If you would also like to use Eucerin Hyaluron-Filler Concentrate in the evening apply it before Eucerin Hyaluron-Filler Night.

Read More

Do's and Dont's

Use this product if …

You want a night cream that supports skin regeneration:
Eucerin Hyaluron-Filler Night Cream is formulated with Dexpanthenol to support the skin's own overnight renewal.

You want to reduce fine lines and wrinkles for a rejuvenated look:
Eucerin Hyaluron-Filler Night has a unique combination of high and low molecular Hyaluronic Acid, Glycine Saponin, and Enoxolone that smooths fine lines and even plumps up deep wrinkles for a rejuvenated look.


Try a different product if …

You’re looking for a night cream for mature skin that plumps up deep wrinkles and improves skin’s elasticity:

 Try Eucerin Hyaluron-Filler + Elasticity Night.

You’re looking for a night cream to combat deep wrinkles, sagging skin and a loss of volume and facial contours:

We recommend Eucerin Hyaluron-Filler + Volume-Lift Night. It plumps up deep wrinkles and redefines facial contours for a lifting effect.

If you have sensitive skin and You’d like to address fine lines and wrinkles:

Try Eucerin Q10 ACTIVE Night Cream with Coenzyme Q10 and a Biotin vitamin complex which reduces the depth of wrinkles and strengthens skin against premature ageing.

You’re looking for a night cream to treat very dry skin and reduce wrinkles:

Try Eucerin Hyaluron-Filler + Urea Night with Natural Moisturising Factors Urea and Hyaluronic Acid.

You’re looking for an anti-ageing product to exfoliate and refine skin texture overnight:

Try Eucerin Hyaluron-Filler Peeling & Night. As well as Hyaluronic Acid and Glycine Saponin it contains an AHA (alpha-hydroxy-acid) Complex. The formula promotes skin cell renewal and refines skin while plumping up even the deepest wrinkles. The product is designed to work during the night. For best results it should be applied before Eucerin Hyaluron-Filler Night.



How it works

How they work together

At the heart of Eucerin’s unique Hyaluron-Filler formula is a unique combination of high and low molecular Hyaluronic Acid:

High molecular Hyaluronic Acid (also known as long-chained Hyaluronic Acid) remains on skin’s surface to improve hydration in the outermost layer of the epidermis – where fine lines and winkles originate.

- The molecules in low molecular Hyaluronic Acid (also known as short-chained Hyaluronic Acid) are 40 times smaller¹ than those of high molecular Hyaluronic Acid and so it is able to penetrate further into the epidermal layers where it stimulates skin’s own production of Hyaluronic Acid.

In most of the formulas, Hyaluronic Acid is combined with bio-active anti-oxidant Glycine Saponin which penetrates even deeper, into the dermal layers of skin, stimulating the production of Hyaluronic Acid and replenishing moisture where deeper wrinkles originate. Furthermore it protects the skin from free radicals.

The next generation Hyaluron-Filler formula also contains Enoxolone, an active ingredient that slows down the degradation rate of skin’s own Hyaluronic Acid by inhibiting Hyaluronidase.

The result: 200% more Hyaluron.
Fine lines and wrinkles are noticeably plumped. For smoother, radiant, and younger looking skin.


¹The standard unit for measuring the mass of an atom is a kilo Dalton (kDa). Long-chained Hyaluronic Acid has a kDa of 2000 and short-chained Hyaluronic Acid has a kDa of 52. Both are contained in the Hyaluron-Filler and Hyaluron-Filler + Elasticity formulas


FAQ (4)

  • How do I know if Eucerin Hyaluron-Filler is the right anti-ageing range for me?


    The Eucerin Hyaluron-Filler range has been specially formulated to tackle the first signs of ageing such as fine lines and wrinkles. While our skin is as individual as we are, and skin ages differently depending on our genetics and lifestyle, these normally start to appear around the age of 30. The products in the Eucerin Hyaluron-Filler range work to counteract the ageing process by plumping up deep wrinkles. For visibly smoother, radiant, and younger looking skin.

    If a loss of volume is your primary concern (as is often the case between the ages of 40 and 50), then the
     Eucerin Hyaluron-Filler + Volume-Lift range has been specially formulated to plump up deep wrinkles and redefine facial contours for a lifting effect. If skin elasticity and deepening wrinkles are your primary concern (most common for those over 50) then we recommend the Eucerin Hyaluron-Filler + Elasticity range.

    For more information on the different stages of 
    skin ageing, and to help you find the right product for you, read our article on facial skin at different ages.


  • At what age should I start using Eucerin Hyaluron-Filler?

    Our skin is as different as we are, so the answer to that question varies from person to person and depends on many factors both internal (such as our genetics) and external (such as the amount of sun our skin has been exposed to). As a general rule, the first signs of aging such as fine lines and wrinkles start to appear in our 30s and that is when we recommend you start using the Eucerin Hyaluron-Filler rangeIf you are in any doubt please read our article on facial skin at different ages or consult a pharmacist or dermatologist.

  • Why do I need a night cream?

    Skin regenerates overnight. As well as moisturising skin, night creams contain ingredients that stimulate the cell regeneration process. In Eucerin Hyaluron-Filler Night that active ingredient is Dexpanthenol which supports skin’s regeneration process overnight. 

  • What is the difference between Eucerin Hyaluron-Filler Night and Eucerin Volume-Filler Night?

    Both are effective anti-aging night creams that are suitable for all skin types. Both also contain Hyaluronic Acid (but in different forms to suit different skin needs) and Dexpanthenol.

    Eucerin Hyaluron-Filler Night also contain Glycine Saponin which supports Hyaluronic Acid production in the dermal layer where the deepest wrinkles form.The focus of this product is on plumping up fine lines and wrinkles. This means that if wrinkles are your primary aging concern then Eucerin Hyaluron-Filler Night is likely to be the most effective treatment for your skin.

    As skin matures further it starts to sag and lose volume and contours. Eucerin Hyaluron-Filler + Volume-Lift Night contains Magnolol – which increases the size and number of volume-boosting cells in skin – and Oligo Peptides to stimulate collagen renewal It plumps up deep wrinkles and redefines facial contours for a lifting effect.

from 104 reviews*
  • Asmaa 08/03/2023
    I would give it a 6 stars if I can
    I have very dry skin that makes me look older than I am, I tired many other products until I found the Urea 5% cream rich night cream which was great but felt I needed to try something else. I have to say this cream is AMAZING! It gets absorbed fast and leaves your skin feeling plumbed, hydrated and soft. You can see difference from the first use but also, after a couple of weeks of usage I can actually see real difference in my whole face. It definitely looks hydrated, soft, plumbed and younger now! My friends tried it for oily skin and had the same result. I am absolutely in love with it. The only downside is that I wish it had urea in it, that would make the perfect moisturizer in my opinion. I currently use it first and then add the rich urea face cream for extra moisture.
  • ChrissieBee 15/12/2022
    Fabulous results!
    Free sample provided
    I used this product not expecting much, but boy, was I pleasantly surprised! The scent is not overpowering, the cream itself is not too heavy feeling on the skin. The cream does take several minutes to be absorbed, though. I noticed a difference in the plumpness of my skin after just one use. Also, the hyperpigmentation that I have had for years has lightened considerably. Very happy with this product, and I will be replacing my previous night cream with Eucerin.
  • Mara9119 25/10/2021
    Brilliant 👏 👏
    Free sample provided
    I could not even imagine that Eucerin would have such wonderful product. This is just fantastic! I could see the difference after the first application. I used it as night cream. It really does what it said on the box.
  • Load More

Popular Products

Our brand values

Pioneers in skincare

We deliver a holistic dermo-cosmetic approach to protect your skin, keep it healthy and radiant.

Recommended by dermatologists

We work together with leading dermatologist and pharmacist partners around the world to create innovative and effective skincare products they can trust and recommend.

Committed to innovation

For over 100 years, we have dedicated ourselves to researching and innovating in the field of skin science. We believe in creating active ingredients and soothing formulas with high tolerability that work to help you live your life better each day.

Find your nearest Eucerin pharmacy